The Song lab

Liu X.#, Shen J.#, Xie L., Wei Z., Wong C., Li Y., Zheng X., Li P. and Song Y.* (2020) Mitotic implantation of a transcription factor via phase separation drives terminal neuronal differentiation. Developmental Cell, 52(3), 277-293; doi.org/10.1016/j.devcel.2019.11.019 [Featured article]

  Highlighted in Developmental Cell: Bonnay F. and Knoblich J.A.* (2020) Prospero Phase-Separating the Way to Neuronal Differentiation. Developmental Cell, 52(3), 251-252. 

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Li B.#, Wong C.#, Gao S.M., Zhang R., Sun R., Li Y. and Song Y.* (2018) The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking. Elife, 2018;7;e38181. doi: 10.7554/eLife.38181

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Xu K., Liu X., Wang Y., Wong C., and Song Y.* (2018) Temporospatial induction of homeo-domain gene cut dictates natural lineage reprogramming. Elife, 2018;7:e33934. 

doi: 10.7554/eLife.33934.                            

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Liu K., Shen D., Shen J., Gao S.M., Li B., Wong C., Feng W. and Song Y.* (2017) The super elongation complex drives neural stem cell fate commitment. Developmental Cell, 40(6), 537-551 [Cover story]. doi: 10.1016/j.devcel.2017.02.022.　　
 Highlighted in Developmental Cell: Rossi A.M. and Desplan C.* (2017) Asymmetric Notch Amplification to Secure Stem Cell Identity. Developmental Cell, 40(6), 513-514. 
  Recommended by F1000Prime: https://f1000.com/prime/727458399

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Lee K.S.#, Wu Z.#, Song Y., Mitra S.S., Feroze A.H., Cheshier S.H., Lu B.* (2013) Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway. Genes & Development, 27(24):2642-7 (#contribute equally) [Cover story]. doi: 10.1101/gad.225169.113.

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Song Y. and Lu B.* (2012) Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells. Journal of Biological Chemistry, 287(21):17716-28. doi: 10.1074/jbc.M112.360719.　

　

Song Y. and Lu B.* (2011) Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes & Development, 25(24):2644-2658. doi: 10.1101/gad.171959.111.　

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Song Y.* (2022). It takes two to tango: The dance of cell fate specification. Developmental Biology, 490:125. (Editorial for a Special Issue on Transcriptional and epigenetic control of cell fate specification)   doi.org/10.1016/j.ydbio.2022.07.011

 

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Liu K., Xu K. and Song Y.* (2019). Faster, Higher, Stronger: Timely and robust cell fate/identity commitment in stem cell lineages. Open Biology, 9:180243. (Invited review)     doi.org/10.1098/rsob.180243 

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Jing M., Zhang P., Wang G., Jiang H., Mesik L., Feng J., Wang S., Looby J., Guagliardo N.A., Langma L.W., Lu J., Zuo Y., Talmage D.A., Role L.W., Barrett P.Q., Zhang L.I., Luo M., Song Y., Zhu J.* and Li Y.* (2018). A genetically-encoded fluorescent acetylcholine indicator for in vitro and in vivo studies. Nature Biotechnology doi: 10.1038/nbt.4184

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Wu Y.C., Lee K.S., Song Y., Gehrke S., Lu B.* (2017) The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain. PLoS Genetics, 13(5):e1006785. doi: 10.1371/journal.pgen.1006785.

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Ouyang Y.#, Song Y.# and Lu B.* (2011) dp53 restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and Cyclin E. PLoS ONE, 6(11):e28098 (# contribute equally). doi: 10.1371/journal.pone.0028098.

 

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Yu L., Song Y. and Wharton R.P.* (2010) E(nos)/CG4699 required for nanos function in the female germ line of Drosophila. Genesis, 48(3):161-70. [Cover story]. doi: 10.1002/dvg.20600.

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Song Y., Fee L., Lee T. and Wharton R.P.* (2007) The molecular chaperone Hsp90 is required for mRNA localization in Drosophila melanogaster embryos. Genetics, 176(4):2213-22. doi.org/10.1534/genetics.107.071472